benzyl alcohol toxicity in adults

Ingredient Watch List: Benzyl Alcohol Another Irritating

Benzyl alcohol had been used for years before that to flush out intravenous or arterial catheters after blood samples were drawn and that exposure to preservative flush be limited to no more than 30 mL for adults per day Benzyl Alcohol actually seems to be among a few that has low toxicity and some preservative action as well

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Optimization of Benzyl Alcohol production via

Optimization of Benzyl Alcohol production via biotransformation of benzaldehyde using free cell of Saccharomyces cerevisiae in presence low toxicity and low vapor pressure Optimization of Benzyl Alcohol production via biotransformation of benzaldehyde using free cell of Saccharomyces cerevisiae in presence the -Cyclodextrin

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Benzyl alcohol

Benzyl Alcohol is a colorless liquid with a sharp burning taste and slight odor It is used as a local anesthetic and to reduce pain associated with Lidocaine injection Also it is used in the manufacture of other benzyl compounds as a pharmaceutical aid and in perfumery and flavoring

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Benzyl alcohol metabolism and elimination in neonates

These results indicate that hippuric acid formation is deficient in preterm neonates Although we did not encounter in our patients the specific toxic signs described as part of the benzyl alcohol toxicity syndrome we cannot directly answer the issue of safety of 'low doses' of benzyl alcohol as found in some medications administered to neonates

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CONTAINS BENZYL ALCOHOL

total amount of benzyl alcohol administered The amount of benzyl alcohol at which toxicity may occur is not known If the patient requires more than the recommended dosages or other medications containing this preservative the practitioner must consider the daily metabolic load of benzyl alcohol from these combined sources (see PRECAUTIONS

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Toxicity of benzyl alcohol in adult and neonatal mice

8-4-2020Benzyl alcohol (BA) is an aromatic alcohol which is used as a bacteriostat in a variety of parenteral preparations In 1982 it was implicated as the agent responsible for precipitating The Gasping Syndrome in premature neonates The investigate further this toxicity BA was administered

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Benzyl

According to the health and wellness website Sixwise some of the most harmful ingredients in dryer sheets and liquid fabric softener alike include benzyl acetate (linked to pancreatic cancer) benzyl alcohol (an upper respiratory tract irritant) ethanol (linked to central nervous system disorders) limonene (a known carcinogen) and chloroform (a neurotoxin and

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Toxicity of benzyl alcohol in adult and neonatal mice

8-4-2020Benzyl alcohol (BA) is an aromatic alcohol which is used as a bacteriostat in a variety of parenteral preparations In 1982 it was implicated as the agent responsible for precipitating The Gasping Syndrome in premature neonates The investigate further this toxicity BA was administered

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Material Safety Data Sheet Benzyl alcohol

Benzyl alcohol contaminated with 1 4% hydrogen bromide and 1 2% of d issolved iron (II) polymerizes Toxicity of the Products of Biodegradation: The products of degradation are less toxic than the product itself Special Remarks on the Products of Biodegradation: Not available

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Benzyl alcohol metabolism and elimination in neonates

These results indicate that hippuric acid formation is deficient in preterm neonates Although we did not encounter in our patients the specific toxic signs described as part of the benzyl alcohol toxicity syndrome we cannot directly answer the issue of safety of 'low doses' of benzyl alcohol as found in some medications administered to neonates

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Bacteriostatic Saline Containing Benzyl Alcohol

Benzyl alcohol is an aromatic alcohol with a structure dissimilar to either the amide or ester local anesthetics Toxicity studies performed on animals suggest that the contents of a 30-mL vial of 0 9% benzyl alcohol could be given to healthy adult patients without any problems and that toxic effects are less than other local anesthetics

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Questions and Answers on Benzyl alcohol in the context of

1 23 January 2014 2 EMA/CHMP/508188/2013 3 Committee for Human Medicinal Products (CHMP) 4 Questions and Answers on Benzyl alcohol in the context 5 of the revision of the guideline on 'Excipients in the label 6 and package leaflet of medicinal products for human use' 7 (CPMP/463/00) 8 Draft 9 Draft agreed by Excipients Drafting group

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SOLU

The amount of benzyl alcohol from medications is usually considered negligible compared to that received in flush solutions containing benzyl alcohol Administration of high dosages of medications containing this preservative must take into account the total amount of benzyl alcohol administered The amount of benzyl alcohol at which toxicity

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Benzyl alcohol and benzoic acid group used as excipients

Benzyl alcohol and benzoic acid group used as excipients Conclusion regarding the toxicity of benzyl alcohol Indeed there is a greater accumulation of benzyl alcohol in serum of pre-term neonates expressed in peak level and in area under curve than in full-term neonates

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Interactions Benzyl Alcohol Bacterial Endotoxin

Combination: benzyl 1 8 + 0 20 None 13/20 alcohol + endotoxin Diazepam 1/20d Naloxone 1/20d a Data represent the results of three experiments for benzyl alcohol and two experiments each for endotoxin and the combina-tion b Mice were given diazepam or naloxone (5 mg/kg i p ) 30 min before treatment with benzyl alcohol endotoxin or the combina

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