Imaging of Long

-Aminoisobutyric acid (AIB) is a nonmetabolized amino acid analogue of alanine which at low ( M) concentrations acts as a tracer for amino acid movements At high concentrations (mM) it competitively inhibits membrane transport and metabolism of protein amino acids and acts as a systemic translocated inhibitor of mycelial extension in fungi

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Concentration and variability of the AIB amino acid in

We found the non-protein amino acid α-amino isobutyric acid (AIB) in one of our samples The non-detection of this amino acid in the other samples analyzed suggests that there are amino acid-containing and amino acid-free MMs with ˜14% of the MMs containing AIB Since the MF of MMs is much higher than that of carbonaceous chondrites (CMs

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Left

tiary amino acid L-Val induces a left handed Type II β-turn in both the solid state and in solution while the cor-responding quaternary amino acid L-α-methylvaline induces a right handed Type III β-turn Introduction* Oligomers of the achiral quaternary α-amino acid Aib (2-aminoisobutyric acid) adopt helical conformations in

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Microwave Assisted SPPS of Hindered Non

1-3 The synthesis of peptides including Aib or N-methylated amino acids has proved challenging however the steric hindrance introduced by the second methyl group whether on the α-carbon or the amide nitrogen makes coupling these amino acid derivatives difficult in conventional SPPS Figure 1 Sterically-hindered non-standard amino acids

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Conformational Manifold of α

Replacement of the α-proton of an alanine residue to generate α-aminoisobutyric acid (Aib) in alanine-based oligopeptides favors the formation of a 310 helix when the length of the oligopeptide is about four to six residues This research was aimed at experimentally identifying the structural impact of an individual Aib residue in an alanine context of short peptides in water and Aib

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2

HMDB is offered to the public as a freely available resource Use and re-distribution of the data in whole or in part for commercial purposes requires explicit permission of the authors and explicit acknowledgment of the source material (HMDB) and the original publication (see the

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Concentration and variability of the AIB amino acid in

Concentration and variability of the AIB amino acid in polar micrometeorites: Implications for the exogenous delivery of amino acids to the primitive Earth G MATRAJT 1 2 S PIZZARELLO 3 S TAYLOR 4 and D BROWNLEE1 1Department of Astronomy University of Washington Seattle Washington 98195 USA

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2

HMDB is offered to the public as a freely available resource Use and re-distribution of the data in whole or in part for commercial purposes requires explicit permission of the authors and explicit acknowledgment of the source material (HMDB) and the original publication (see the

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THE USE OF D

amino acids in peptide design because they can adopt conformations on both sides of the φ-ψ map While the achiral Gly and Aib residues can support conformations with both positive and negative values of φ D-amino acids may be used in design when positive φ values are required to form a desired structure 3 β-HAIRPIN DESIGN

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2 Amino 2 Methylpropionic Acid

When the cells are incubated for 24 hours in serum-free medium the kinetics of AIB uptake show that there is hardly if any affinity of the amino acid to the carrier system as can be seen from Fig 11 This means that the entry of AIB into cells under these conditions occurs only by diffusion

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Conformational Manifold of r

investigated several Aib-based aliphatic peptides of intermediate size in organic solvents and obtained a very thermostable 310-structure 14 De Filippis et al confirmed and explained the thermostability of Aib with the reduction of entropy of this amino acid residue in the unfolded state 15 Numerous studies

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Concentration and variability of the AIB amino acid in

We found the non-protein amino acid α-amino isobutyric acid (AIB) in one of our samples The non-detection of this amino acid in the other samples analyzed suggests that there are amino acid-containing and amino acid-free MMs with ˜14% of the MMs containing AIB Since the MF of MMs is much higher than that of carbonaceous chondrites (CMs

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Regulation of Amino Acid Transport Systems by Amino Acid

Regulation of Amino Acid Transport Systems by Amino Acid Depletion and Supplementation in Monolayer Cultures of Rat Hepatocytes" (Received for publication June 12 1978) Darshan S Kelley and Van R Potter From the McArdle Laboratory for Cancer Research University of Wisconsin Madison Wisconsin 53706

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DDBJ Codes Used in Sequence Description

Feature Table Definition: 7 4 3 Amino acid abbreviations Modified and Unusual Amino Acids For other amino acids those that are not included in Amino Acid Codes abbreviation listed below is used All of these amino acids are described with one letter abbreviation X in /translation qualifier of CDS feature

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Regulation of Amino Acid Transport Systems by Amino Acid

Regulation of Amino Acid Transport Systems by Amino Acid Depletion and Supplementation in Monolayer Cultures of Rat Hepatocytes" (Received for publication June 12 1978) Darshan S Kelley and Van R Potter From the McArdle Laboratory for Cancer Research University of Wisconsin Madison Wisconsin 53706

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DDBJ Codes Used in Sequence Description

Feature Table Definition: 7 4 3 Amino acid abbreviations Modified and Unusual Amino Acids For other amino acids those that are not included in Amino Acid Codes abbreviation listed below is used All of these amino acids are described with one letter abbreviation X in /translation qualifier of CDS feature

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